Electrochemical Detection of a Local Anesthetic Dibucaine at Arrays of Liquid|Liquid MicroInterfaces

Electrochemical characterization and detection of protonated dibucaine (DIC+) at microinterface array across water|1,6-dichlorohexane were performed using cyclic voltammetry (CV) differential pulse (DPV). Some thermodynamic parameters dibucaine, such as the standard transfer potential, Gibbs energy partition coefficient, estimated by CV. In addition to analytical parameters, impact bovine serum albumin (BSA) on (in artificial matrices) was also investigated. DPV applied detect a lower concentration DIC+, resulting in limit 0.9 ± 0.06 µM. While presence BSA affected CV, demonstrated reduced current responses, confirmed be an efficient method for lowering concentrations matrix BSA, with (LOD) 1.9 0.12